Rheumatoid Nodulosis in an Adult Patient Negative for Rheumatoid Factor

Palmar rheumatoid nodulosis associated with local pressure.

Rheumatoid nodulosis is a term used to describe adult patients with rheumatoid arthritis with little or no clinical joint inflammation who have numerous subcutaneous nodules indistinguishable from those of patients with active rheumatoid arthritis. This paper reports the case of a woman with quiescent rheumatoid arthritis who developed palmar nodulosis three weeks after the strenuous activity o...

Rheumatoid arthritis in an adult patient with mosaic distal 18q-,

Ring chromosome 18 has a highly variable phenotype, depending on the extent of distal arm deletions. It is most commonly presented as a combination of 18pand distal 18qsyndrome. IgA deficiency and autoimmune diseases have been previously described in these patients. Seven cases of juvenile rheumatoid arthritis (JRA) have been reported. Here we report the first case of late onset rheumatoid arth...

Rheumatoid arthritis in an adult patient with mosaic distal 18q-,

Ring chromosome 18 has a highly variable phenotype, depending on the extent of distal arm deletions. It is most commonly presented as a combination of 18pand distal 18qsyndrome. IgA deficiency and autoimmune diseases have been previously described in these patients. Seven cases of juvenile rheumatoid arthritis (JRA) have been reported. Here we report the first case of late onset rheumatoid arth...

Methotrexate-induced accelerated nodulosis in seropositive rheumatoid arthritis.

A 57 year old gentleman presented with multiple nodular swellings over dorsal aspects of hands (Figure 1), forearms (Figure 2), posterior superior iliac spine and over back (Figure 2) for last two weeks. He was diagnosed with seropositive rheumatoid arthritis (rA) 6 months back and was put on weekly subcutaneous methotrexate (MTX) and oral sulphasalazine. The patient did not notice any nodule d...

Methotrexate-induced accelerated nodulosis in a patient with rheumatoid arthritis and scleroderma.